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Mathematical model of excitation-contraction in a uterine smooth muscle cell

journal contribution
posted on 27.10.2021, 20:31 by Weiwei Ai, Limor Freifeld, David NickersonDavid Nickerson
The Bursztyn et al. (2007) paper proposes a mathematical model of excitation-contraction in a myometrial smooth muscle cell (SMC). The model incorporates processes of intracellular Ca^2+ concentration control, myosin light chain (MLC) phosphorylation and stress production. We create a modularized CellML implementation of the model, which is able to simulate these processes against the original data.

Funding

Ministry of Business, Innovation and Employment: 12 Labours

History

Commissions

VI. Molecular & Cellular

ISSN

2744-6204

Journal Title

Physiome